This form must be completed at the end of a research study, not for a protocol that has be determined to be non-research. 

This form must be completed for any changes to a previously approved research project.

This form must be completed if an investigator deviated from a previously IRB approved study without a prior notification request to the IRB

This form must be completed to continue any study past the designated expiration date.  

This form must be completed and reported to the IRB within 48 hours of an adverse event.